Wednesday’s TV highlights

SERIES

Up All Night: While Chris and Reagan (Will Arnett, Christina Applegate) go out for a romantic evening, Ava (Maya Rudolph) takes care of Amy in this new episode (8 p.m. NBC).

Harry’s Law: Harry and Oliver (Kathy Bates, Mark Valley) take on the mayor (George Wendt) of a small town where Harry’s Mercedes is impounded for violating the local “Buy American” law in this new episode (9 p.m. NBC).

Nova: “The Fabric of the Cosmos” continues with “The Illusion of Time,” in which physicist Brian Greene reveals a new way of thinking about time, in which moments past, present and future exist all at once (9 p.m. KOCE). In a second new episode at 10, subtitled “The Elegant Universe,” Greene explores string theory.

Work of Art: The Next Great Artist: The artists visit a major newspaper’s offices, where they’re challenged to find a headline that resonates with them and create a work of art based on the story (9 p.m. Bravo).

Vietnam in HD: The new episode recalls the massive Tet offensive, which caught the Americans by surprise and led to the political unrest and social turmoil of 1968 that helped Nixon win the presidency (9 p.m. History).

Psych: The manager of Santa Barbara’s minor league baseball team hires Shawn and Gus (James Roday, Dule Hill) to investigate the mysterious death of the team’s hitting coach. Wade Boggs and Danny Glover guest star in this new episode (10 p.m. USA).

SPECIALS

Your Money, Your Vote: The Republican Presidential Debate: Candidates discuss jobs, taxes, the deficit and the health of the U.S. economy (5 and 8 p.m. CNBC).

The 45th Annual CMA Awards: Topping the list of nominees are four artists with five nominations each — Jason Aldean, Brad Paisley, Blake Shelton and Taylor Swift — in this new special featuring performances by Aldean, the Band Perry, Shelton, Lionel Richie, Little Big Town, Rascal Flatts, Darius Rucker, Swift and Keith Urban. Co-hosts Paisley and Carrie Underwood will sing their duet “Remind Me (8 p.m. ABC).

SPORTS

Hockey: The Nashville Predators visit the Ducks (7 p.m. FS Prime).